Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
All Product Categories
-
Parasite Related Products (2499)
Related Products (2499)
-
Related Compound Screening Libraries (1)
-
Parasite Isoform Comparison
-
α-Costic acid
0 ImagesCat. No.: HY-N16388CAS No.: 28399-17-9α-Costic acid is a plant sesquiterpene that can induce oxidative stress and autophagy in tomatoes. α-Costic acid has acaricidal activity.
-
Antitrypanosomal agent 4
0 ImagesCat. No.: HY-146049CAS No.: 2456427-48-6Antitrypanosomal agent 4 (compound 19) is a potent and blood-brain barrier permeable antitrypanosomal agent. Antitrypanosomal agent 4 has good activity against Trypanosoma cruzi (T. cruzi) and Trypanosoma brucei brucei (T. b. brucei) with IC50s of 1.2 μM and 70 nM, respectively. Antitrypanosomal agent 4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
-
BiPNQ
0 ImagesCat. No.: HY-121187CAS No.: 313513-16-5BiPNQ is a potent inhibitor of Trypanosoma cruzi, the causative agent of Chagas disease.
-
Parbendazole-d3
0 ImagesCat. No.: HY-115364SCAS No.: 1613439-58-9Synonyms: SKF 2904-d3Parbendazole-d3 is the deuterium labeled Parbendazole. Parbendazole is a potent inhibitor of microtubule assembly, destabilizes tubulin, with an EC50 of 530 nM, and exhibits a broad-spectrum anthelmintic activity.
-
16-Keto Aspergillimide
0 ImagesCat. No.: HY-137141CAS No.: 199784-50-4Synonyms: SB20232716-Keto Aspergillimide (SB202327) is an anthelmintic agent isolated from Aspergillus strain IMI 337664.
-
Moxipraquine
0 ImagesCat. No.: HY-107034CAS No.: 23790-08-1Synonyms: 349C59Moxipraquine is a potent insecticide against Trypanosoma cruzi. Moxipraquine effectively inhibits Leishmania major, L. mexicana mexicana and L. brasiliensis panamensis but not L.b. brasiliensis .
-
Antibacterial agent 180
0 ImagesCat. No.: HY-163292CAS No.: 3029324-01-1Antibacterial agent 180 (15g), an appropriate substrate for the type I nitro reductases (TcNTR I), is a promising antitrypanosomatid agent. Antibacterial agent 180 (15g) shows nonmutagenic potential against Salmonella typhimurium strains (TA98, TA100, and TA102).
-
Antileishmanial agent-18
0 ImagesCat. No.: HY-149834CAS No.: 1007567-02-3Antileishmanial agent-18 (Compound 1e) is an antileishmanial agent. Antileishmanial agent-18 effectively inhibits growth of L. donovani promastigotes. Antileishmanial agent-18 is safe for host cells.
-
Tetrandrine (Standard)
0 ImagesSynonyms: NSC-77037 (Standard); d-Tetrandrine (Standard)Tetrandrine (Standard) is the analytical standard of Tetrandrine. This product is intended for research and analytical applications. Tetrandrine (NSC-77037; d-Tetrandrine) is a bis-benzyl-isoquinoline alkaloid, which inhibits voltage-gated Ca2+ current (ICa) and Ca2+-activated K+ current.
-
Hexythiazox-d11
0 ImagesCat. No.: HY-B1851SCAS No.: 2714418-33-2Hexythiazox-d11 is deuterium labeled Hexythiazox. Hexythiazox is a selective acaricide with ovicidal, larvicidal and nymphicidal activities. Hexythiazox is widely used for chemical control of mites on cotton, fruits and vegetables. Hexythiazox is harmless to mammals and has no effect on beneficial insects and predators of mites.
-
Methyl Clonazepam-d3
0 ImagesCat. No.: HY-W740297CAS No.: 1189992-73-1Methyl Clonazepam-d3 is the deuterium labeled Methylclonazepam (HY-W399186). Methylclonazepam is a benzodiazepine with anxiolytic activity. Methylclonazepam inhibits the absorption of 5-hydroxytryptamine by Schistosoma mansoni. Methylclonazepam derivatives have anti-Schistosoma mansoni activity.
-
Antimalarial agent 29
0 ImagesCat. No.: HY-155688CAS No.: 2821078-81-1Antimalarial agent 29 (compound 16) is an antimalarial agent that inhibits P. berghei liver stage parasite load with an EC50 of 5.2 μM.
-
Antiparasitic agent-4
0 ImagesCat. No.: HY-146042CAS No.: 2253996-66-4Antiparasitic agent-4 (compound 4q) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 8.51 μM and 2.20 μM, respectively. Antiparasitic agent-4 also has certain cytotoxicity against HepG2 (CC50 = 18.97 μM).
-
DDD01035881
0 ImagesCat. No.: HY-187123CAS No.: 1396858-56-2DDD01035881 is a Plasmodium falciparum Pfs16 inhibitor, with an EC50 of 130 nM for exflagellation of male gametes of Plasmodium falciparum NF54 gametocytes. DDD01035881 stabilizes mature activated male gametocyte Pfs16, mimics the Pfs16-deficient phenotype, blocks the early formation process of male gametes before DNA replication, inhibits exflagellation, and exhibits male-specific activity with no activity against female gametes or asexual malaria parasite stages. DDD01035881 can be used in malaria-related research.
-
DNMT-IN-3
0 ImagesCat. No.: HY-149289CAS No.: 1683516-27-9DNMT-IN-3 is an DNA Methyltransferase (DNMT) inhibitor, and plays an antimalarial role with IC50 of 60 nM against Plasmodium falciparum (Plasmodium). DNMT-IN-3 can be used for malaria related research.
-
Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2
0 ImagesCat. No.: HY-P10215Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent Plasmodium subtilisin-like protease 1 (SUB1) inhibitor. SUB1-IN-1 shows IC50 values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively.
-
TSO-13
0 ImagesCat. No.: HY-172206TSO-13 is the inhibitor for the main cysteine protease of Trypanosoma cruzi Cruzipain with an IC50 of 2.2 μM. TSO-13 inhibits T. cruzi in Vero cell with an IC50 of 1.9 μM.
-
Clindamycin phosphate (Standard)
0 ImagesSynonyms: Clindamycin 2-phosphate (Standard); U-28508 (Standard)Clindamycin phosphate (Standard) is the analytical standard of Clindamycin phosphate. This product is intended for research and analytical applications. Clindamycin phosphate (Clindamycin 2-phosphate) is a broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin phosphate is the proagent of Clindamycin (HY-B1455) with no antimicrobial activity in vitro but can be rapidly converted in vivo to the active parent agent, Clindamycin, by phosphatase ester hydrolysis. Clindamycin phosphate can be used for researching acne and bacterial vaginosis.
-
DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS
0 ImagesCat. No.: HY-D1532CAS No.: 263718-22-5DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS is a fluorescent dye, and can be applied in a fluorogenic substrate for an aspartyl proteinase from human malaria parasite.
